Birth Chart and Horoscope of Irvine alumni
- Ai (poet)
- Alice Sebold
- Amber Neben
- Amitabh Joshi
- Armand Marie Leroi
- Bob Gunton
- Brad Evans
- Brigitte Jordan
- Brittany Hayes
- Byeong Sam Jeon
- Byron Velvick
- Chelsea Cain
- Chris Kelly (writer)
- Christopher Jargocki
- Clara Chung
- Dan Fredinburg
- Dave Bass
- Durbin Feeling
- Eby Friedman
- Elise Blackwell
- Erin Gruwell
- Étienne Wenger
- Fardad Fateri
- Gary Figueroa
- Greg Louganis
- Gregg Lambert
- Heidi King
- Hulleah Tsinhnahjinnie
- James LeGros
- James Luna
- Janet Nguyen
- Jill Ciment
- Jillian Kraus
- Jim McCormick (author)
- Joan Petersilia
- Joe Lacob
- John Langley
- John Tracy (aerospace executive)
- Johnny Lu
- Jonny Bogris
- Jose Solorio
- Joshua Ferris
- Joslyn Davis
- Kelly Fremon Craig
- Leon J. LaPorte
- Lilan Bowden
- Lisa Marie Scott
- Lára Hrund Bjargardóttir
- Maile Meloy
- Marcia Hafif
- Marilyn Sheppard
- Mark Gibbons
- Mark Keam
- Masanobu Shinozuka
- McG
- Melissa King (chef)
- Michael A. Rice
- Michael Chabon
- Michael D. Newcomb
- Michael Ramirez
- Mike Powell (long jumper)
- Nazanin Boniadi
- Nevada Barr
- Paul J. Nahin
- Paul Mockapetris
- Peter M. Rhee
- Phil Tippett
- Polly Matzinger
- Richard T. Wright
- Rick Hoberg
- Sam Sheppard
- Sherod Santos
- Sophie Oda
- Subhash Chandra Lakhotia
- SwizZz
- Tangi Miller
- Thuy Trang
- Tom Martin (writer)
- Toshiki Tajima
- Van Tran
- Veena Tandon
- William K. Black
- Wright Massey